potassium tert butoxide suppliers wholesale

Product Description

Potassium tert-butoxide, often abbreviated as KOt-Bu, is a chemical compound with the molecular formula KOC(CH3)3. It is a strong, non-nucleophilic base derived from tert-butanol (2-methyl-2-propanol) and potassium metal. Here’s a detailed description of potassium tert-butoxide:

Chemical Structure:

• Potassium tert-butoxide consists of a potassium ion (K+) bonded to a tert-butoxide ion (OC(CH3)3-). The tert-butoxide ion is an alkoxide, characterized by the presence of an oxygen atom bonded to a carbon atom that is further attached to three methyl groups.

Physical Properties:

• Appearance: Potassium tert-butoxide is typically found as a white or off-white crystalline powder.
• Solubility: It is sparingly soluble in non-polar solvents like hydrocarbons but more soluble in polar solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF).
• Stability: It should be stored under anhydrous (water-free) conditions and protected from moisture and air since it can react with water and air moisture.

Chemical Properties and Uses:

1. Strong Base: Potassium tert-butoxide is a strong base, meaning it readily accepts protons (H+) in chemical reactions. It is commonly used in organic synthesis to initiate various reactions by deprotonating acidic hydrogens.
2. Elimination Reactions: It is often employed in elimination reactions, such as the E2 elimination, where it removes a proton from a β-carbon, resulting in the formation of an alkene.
3. Condensation Reactions: Potassium tert-butoxide can also be used in condensation reactions to promote the formation of carbon-carbon or carbon-heteroatom bonds.
4. As a Strong Base in Organic Synthesis: Due to its non-nucleophilic nature, it is favored in reactions where nucleophilic attack is not desired.

Applications:

• Potassium tert-butoxide is widely used in the synthesis of organic compounds, particularly in the pharmaceutical and chemical industries.
• It is employed in the production of specialty chemicals, such as pharmaceutical intermediates and agrochemicals.
• It plays a vital role in the synthesis of various plastics, rubber, and polymers by initiating polymerization reactions.
• In the field of organometallic chemistry, it is used to generate highly reactive species for coupling reactions and catalyst synthesis.

Safety Considerations:

• Potassium tert-butoxide is a strong base and can be corrosive. Proper precautions, including the use of personal protective equipment, should be taken when handling it.
• It reacts violently with water, releasing flammable gases, so it should be stored and handled in anhydrous conditions.

In summary, potassium tert-butoxide is a potent and versatile chemical reagent used in various chemical reactions, particularly in organic synthesis and the production of specialty chemicals and polymers. Its strong basicity and non-nucleophilic character make it a valuable tool for chemists in a wide range of applications.

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